Produced in the body as a mechanism to cope with inflammation and pain, palmitoylethanolamide or PEA has many other intriguing health benefits too. People consider taking Palmitoylethanolamide as according to some scientists, nerves can be protected and natural cannabinoids can receive a boost through the fatty acid that is PEA.
Overview of PEA
Palmitoylethanolamide was discovered in the 1950s, and since then medical researchers have often carried some curious studies on its benefits and mechanism of action. The most prominent benefits, though not supported by adequate research are, are that of anti-inflammation and painkilling. It is now being talked about that PEA can also help with chronic and neuropathic pain.
It is a fatty acid similar to the anandamide which is the prominent cannabinoid receptor molecule produced by the body. Fatty acids contain amides and thus, fatty acids such as PEA and cannabinoids have an impact on nerve communication.
There have also been studies to ascertain its effect on complex pain. However, the most eye-catching ones have been around its role in activation of cannabinoid receptors. Thus, for brain support, heart health, and immunity, many people consider taking palmitoylethanolamide supplement. There is limited research regarding all these purported benefits, and according to some, the research that is already there is not very sound
Besides humans, palmitoylethanolamide is also produced in many plants and animals. Its highest contents are found in the following:
- Egg yolk,
- Peanuts, and
Effects of PEA
There are many purported health benefits of taking palmitoylethanolamide supplement, but the main one that is backed by more study and research than any other health benefit is that of pain management.
It has been studied that PEA can decently reduce pain, including chronic pain as well as neuropathic pain. According to these studies, the effect of palmitoylethanolamide on pain is experienced in a minimum period of 2 weeks. In the studies, it was given in doses ranging from 300 to 1200 mg per day for 3-8 weeks. It should be noted that the effects are more pronounced if it is taken for over 8 weeks.
Participants of the studies had a considerable reduction in their sciatic pain and that in their lower backs. Many of them were relieved of the need of taking any other pain killers.
Studies conducted on women with pelvic pain showed that it alleviated pain and had a positive effect on sexual function for more than 6 months. Other studies were also conducted to study its effect on arthritis pain, cancer pain, pain from fibromyalgia, etc.
PEA as a supplement
Palmitoylethanolamide supplement is regarded as a supplement for diet, and commonly such supplements are not backed by sound researches. Likewise, the PEA supplement like pyrroloquinoline quinone supplement is also not validated by the FDA yet. There are manufacturing standards required by the regulations, but before taking these, you must communicate regarding this with your doctor,
PEA supplement can be taken through tablets, powdered forms, or capsules. Beware of taking supplements that are based on synthetic origin, as these are regarded as unapproved drugs by the FDA.